References for 2024 Poster by Pelumi M. Oladipo and Jeffrey L. Ram, Wayne State University, Detroit, MI USA
"Not so Cryptic Anymore: Genetic and Functional Differences of Escherichia marmotae from E. coli"
Background
Escherichia marmotae is an emergent member of the Escherichia cryptic clades that were first isolated from animal feces and environmental waters (Walk et al., 2009; Ram et al., 2007; Liu et al., 2015). E. marmotae recently gained scientific prominence due to its association with human infections including sepsis, pyelonephritis and spondylodiscitis (Sivertsen et al., 2022; Sinha et al., 2023). Due to its phenotypic resemblance to E. coli but distinct genome, with a 10% pairwise difference from E. coli of its whole genome sequence (illustrated above), the significance of E. marmotae as a pathogen may be underestimated. Given its potential as a human pathogen, sensitive, specific, and rapid identification techniques for E. marmotae are urgently needed to understand its functional capabilities, pathogenicity, and prevalence.
Liu S, Jin D, Lan RT, Wang YT, Meng Q, Dai H, Lu S, Hu SK, Xu JG. 2015. Escherichia marmotae sp nov., isolated from faeces of Marmota himalayana. International Journal of Systematic and Evolutionary Microbiology 65: 2130-2134. https://doi.org/10.1099/ijs.0.000228
Ram JL, Thompson B, Turner C, Nechvatal JM, Sheehan H, Bobrin J. 2007. Identification of pets and raccoons as sources of bacterial contamination of urban storm sewers using a sequence-based bacterial source tracking method. Water Research 41(16): 3605-3614.
https://doi.org/10.1016/j.watres.2007.04.013
Sinha T, Merlino J, Rizzo S, Gatley A, Siarakas S, Gray T. 2023. Unrecognised: isolation of Escherichia marmotae from clinical urine sample, phenotypically similar to Escherichia coli. Pathology. https://doi.org/10.1016/j.pathol.2023.08.015
Sivertsen A, Dyrhovden R, Tellevik MG, Bruvold TS, Nybakken E, Skutlaberg DH, Skarstein I, Kommedal O. 2022. Escherichia marmotae-a Human Pathogen Easily Misidentified as Escherichia coli. Microbiology Spectrum 10(2). https://doi.org/10.1128/spectrum.02035-21
Walk ST, Alm EW, Gordon DM, Ram JL, Toranzos GA, Tiedje JM, Whittam TS. 2009. Cryptic Lineages of the Genus Escherichia. Applied and Environmental Microbiology 75(20): 6534-6544.https://doi.org/10.1128/AEM.01262-09
The poster can be viewed by clicking here: poster
"Not so Cryptic Anymore: Genetic and Functional Differences of Escherichia marmotae from E. coli"
Background
Escherichia marmotae is an emergent member of the Escherichia cryptic clades that were first isolated from animal feces and environmental waters (Walk et al., 2009; Ram et al., 2007; Liu et al., 2015). E. marmotae recently gained scientific prominence due to its association with human infections including sepsis, pyelonephritis and spondylodiscitis (Sivertsen et al., 2022; Sinha et al., 2023). Due to its phenotypic resemblance to E. coli but distinct genome, with a 10% pairwise difference from E. coli of its whole genome sequence (illustrated above), the significance of E. marmotae as a pathogen may be underestimated. Given its potential as a human pathogen, sensitive, specific, and rapid identification techniques for E. marmotae are urgently needed to understand its functional capabilities, pathogenicity, and prevalence.
Liu S, Jin D, Lan RT, Wang YT, Meng Q, Dai H, Lu S, Hu SK, Xu JG. 2015. Escherichia marmotae sp nov., isolated from faeces of Marmota himalayana. International Journal of Systematic and Evolutionary Microbiology 65: 2130-2134. https://doi.org/10.1099/ijs.0.000228
Ram JL, Thompson B, Turner C, Nechvatal JM, Sheehan H, Bobrin J. 2007. Identification of pets and raccoons as sources of bacterial contamination of urban storm sewers using a sequence-based bacterial source tracking method. Water Research 41(16): 3605-3614.
https://doi.org/10.1016/j.watres.2007.04.013
Sinha T, Merlino J, Rizzo S, Gatley A, Siarakas S, Gray T. 2023. Unrecognised: isolation of Escherichia marmotae from clinical urine sample, phenotypically similar to Escherichia coli. Pathology. https://doi.org/10.1016/j.pathol.2023.08.015
Sivertsen A, Dyrhovden R, Tellevik MG, Bruvold TS, Nybakken E, Skutlaberg DH, Skarstein I, Kommedal O. 2022. Escherichia marmotae-a Human Pathogen Easily Misidentified as Escherichia coli. Microbiology Spectrum 10(2). https://doi.org/10.1128/spectrum.02035-21
Walk ST, Alm EW, Gordon DM, Ram JL, Toranzos GA, Tiedje JM, Whittam TS. 2009. Cryptic Lineages of the Genus Escherichia. Applied and Environmental Microbiology 75(20): 6534-6544.https://doi.org/10.1128/AEM.01262-09
The poster can be viewed by clicking here: poster